Recombinant Collagen Barrier Repair Cream
Recombinant-Collagen-Barrier-Repair-Cream2
Recombinant Collagen Barrier Repair Cream3
Recombinant Collagen Barrier Repair Cream4
Recombinant Collagen Barrier Repair Cream5
Recombinant Collagen Barrier Repair Cream6
Recombinant Collagen Barrier Repair Cream-1
Recombinant Collagen Barrier Repair Cream
Recombinant-Collagen-Barrier-Repair-Cream2
Recombinant Collagen Barrier Repair Cream3
Recombinant Collagen Barrier Repair Cream4
Recombinant Collagen Barrier Repair Cream5
Recombinant Collagen Barrier Repair Cream6
Recombinant Collagen Barrier Repair Cream-1

Recombinant Collagen Barrier Repair Cream

This 4-in-1 powerhouse nourishes, repairs, soothes, and hydrates. It dives deep to strengthen your skin barrier and boost its natural resilience.It locks in moisture for the long haul, smoothing out rough patches for all-day hydration.Meanwhile, it calms sensitivity and redness, eases stinging and burning, and speeds up your skin's self-repair for a stronger, more stable barrier.
  • [Collagen] A 4-in-1 blend of nourishing, repairing, soothing, and hydrating benefits that deeply fortifies the barrier and boosts resilience.
  • [Sodium Hyaluronate] Locks in long-lasting moisture, smoothing out dryness and roughness for all-day hydration.
  • [Panthenol] Soothes sensitivity and redness, taking the edge off stinging and burning sensations.
  • [Centella Asiatica Extract] Accelerates skin recovery for a healthier, more stable barrier.
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Product Details

Product ID CREAM-H-005
Key Benefits Nourishing + Repairing + Moisturizing + Soothing
Target Audience women&men skincare
Package 1 box*1.76 oz/50g
Shelf life 3 years
MOQ 50kg
Delivery Time 40-60 days(Once the design draft is finalized)

 

Key Ingredients

Aqua, Butylene Glycol, Glycerin, Dimethicone, Squalane, Cyclopentasiloxane, Cetearyl Alcohol, Behenyl Alcohol, Pentylene Glycol, Tocopheryl Acetate, Hydrogenated Lecithin, Arginine, Carbomer, Hexylene Glycol, Hydroxyacetophenone, Panthenol, Collagen, Trehalose, Centella Asiatica Flower/Leaf/Stem Extract, Xanthan Gum, Disodium EDTA, Ethyl Ascorbyl Ether, Niacinamide, Sodium Hyaluronate

Suitable for

For those with dry, sensitive skin; Compromised skin barrier; Prone to recurring redness; In need of all-day nourishment and repair

Product Efficacy Report

  1. Soothing Nourishing

Test Protocol: This study evaluated 31 male and female subjects with sensitive skin (confirmed by a positive lactic acid sting test score of ≥3) who exhibited a dull, uneven skin texture and facial redness. The analysis included 31 valid subjects, yielding an efficacy rate of 93.94%. By measuring changes—before and after using the test product—in skin hemoglobin (EI value), smoothness (SEsm value), roughness (SEr value), radiance, percentage of red-zone area, redness score, mean erythema value, dermal thickness, blood perfusion, and core temperature, alongside subject self-assessments, the study verified claims regarding the product’s soothing and nourishing properties, cooling effect, ability to improve skin density and thickness, and its gentle, non-irritating nature suitable for sensitive skin.

 

Skin transepidermal water loss (TEWL) value
After 14 days There was a significant difference in the skin hemoglobin EI value; the rate of change in the skin hemoglobin EI value compared to the baseline was -13.42%.
After 28 days There was a significant difference in the skin hemoglobin EI value; the rate of change in the skin hemoglobin EI value compared to the baseline was -14.06%.
Blood perfusion volume
After 14 days There was a significant difference in blood perfusion; the rate of change in blood perfusion compared to the baseline value was -12.53%.
After 28 days There was no significant difference in blood perfusion values; the rate of change in blood perfusion relative to the baseline value was -2.56%.
Conclusion The results indicate that the test samples provide soothing effects after 14 and 28 days of use.
Skin smoothness SEsm value
After 14 days There was a significant difference in the skin smoothness SEsm value, and the rate of change in the SEsm value compared to the baseline was -26.56%.
After 28 days There was a significant difference in the skin smoothness SEsm value, and the rate of change in the SEsm value compared to the baseline was -24.10%.
Skin Roughness SEr Value
After 14 days There was no significant difference in the SEr value of skin roughness; the rate of change in the SEr value compared to the baseline was 5.48%.
After 28 days There was a significant difference in the skin roughness SEr value, and the rate of change in the SEr value compared to the baseline was 21.91%.
Skin Radiance
After 14 days The rate of change in skin glossiness compared to the baseline value is 34.22%.
After 28 days The rate of change in skin glossiness compared to the baseline value is 34.76%.
Conclusion The results indicate that the test samples provide nourishing benefits after 14 and 28 days of use.
Area of the Skin’s Red Zone
After 14 days The rate of change in the proportion of the red zone area compared to the baseline value is -27.78%.
After 28 days The rate of change in the proportion of the red zone area compared to the baseline value is -30.07%.
Conclusion The results indicate that the test sample reduced redness after 14 and 28 days of use.
Redness Score
10 Minutes Later The rate of change in the redness score compared to the baseline value is -5.65%.
60 Minutes Later The rate of change in the redness score compared to the baseline value is -5.46%
After 14 days The rate of change in the redness score compared to the baseline value is -13.64%.
After 28 days The rate of change in the redness score compared to the baseline value is -16.48%.
Average Erythema Value
After 14 days The rate of change of the mean erythema value compared to the baseline value was -16.26%.
After 28 days The rate of change of the mean erythema value compared to the baseline value was 12.10%.
Dermal Thickness
After 14 days The rate of change in dermal thickness compared to the baseline value is 22.63%.
After 28 days The rate of change in dermal thickness compared to the baseline value is 22.77%.
Dermal Density
After 14 days The rate of change in dermal density compared to the baseline value is 33.33%.
After 28 days The rate of change in dermal density compared to the baseline value is 50.00%.

 

The basis for determining the validity of the test items involves statistical analysis using statistical software. The test data are subjected to a normality test; if the data follow a normal distribution, a t-test is used for analysis, whereas if they do not, a rank-sum test is employed. The significance level for the statistical methods is set at p < 0.05, indicating statistical significance within a 95% confidence interval.

  1. Repair

Test Protocol: This test evaluated the repair efficacy claims of the submitted sample by measuring specific parameters in 30 healthy Asian (Chinese) subjects (male and female) before and after product application. The study included 30 valid subjects, achieving a 100% validity rate.

 

Skin transepidermal water loss (TEWL) value
2 Hours Later Among the 30 subjects, the rate of change in transepidermal water loss (TEWL) in the treated skin areas was -31.48%, while that in the control areas was -23.03%; a significant difference was observed between the two groups.
4 Hours Later Among the 30 subjects, the rate of change in transepidermal water loss (TEWL) for the skin in the test area was -35.80%, while that for the control area was -24.34%; a significant difference was observed between the two groups.
Conclusion The results indicate that the test samples exhibit repair efficacy after 2 and 4 hours of use.
Skin Hemoglobin EI Value
2 Hours Later The rate of change in the skin hemoglobin EI value in the test area for the 30 subjects was -23.22%, while that in the control area was -12.26%; there was no significant difference between the two groups.
4 Hours Later The rate of change in the skin hemoglobin EI value in the test area for the 30 subjects was -25.84%, while that in the control area was -16.09%; there was no significant difference between the two groups.

 

Statistical analysis was performed using SPSS 26.0. Test data were subjected to a normality test; data following a normal distribution were analyzed using the t-test, while non-normally distributed data were analyzed using the rank-sum test. A significance level of p < 0.05 was adopted, indicating statistical significance within a 95% confidence interval.

Regarding the correlation between the test parameter and the efficacy claim, “repair” refers to the maintenance of the treated area in a normal state; therefore, the repair efficacy of the sample can be evaluated by measuring improvements in Transepidermal Water Loss (TEWL), stratum corneum hydration, or the hemoglobin Erythema Index (EI) before and after product application.

Stratum corneum hydration was measured using the internationally recognized capacitance method, which assesses changes in skin capacitance to determine if stratum corneum hydration has increased; higher measured values ​​indicate higher hydration levels in the stratum corneum following sample application. TEWL serves as an indicator of skin barrier function; a lower TEWL value signifies reduced transepidermal water loss and superior barrier function. A lower hemoglobin EI value indicates a lower hemoglobin content in the skin. The sample is considered to possess repair efficacy if, following application, there is a significant decrease in TEWL and a significant increase in stratum corneum hydration, or a significant decrease in the hemoglobin EI value.

  1. Moisturization

Test Objective: This test establishes an *in vitro* protocol to evaluate the moisturizing efficacy of cosmetics and raw materials by measuring their water-retention capabilities in a dry environment.

*In Vitro* Moisturizing Efficacy Evaluation: Three replicates were set up for each test group. Negative and positive control groups were included alongside the test groups; glycerin was used for the positive control, and purified water for the negative control. The procedure was identical for all groups: A clean, dry, stoppered glass weighing bottle was placed in a desiccator (maintained at 25°C ± 1°C with indicating silica gel desiccant at the bottom) the day before the test, and its weight (m0) was accurately recorded. At room temperature, 1 mL of nutrient agar was pipetted into the weighing bottle; after solidification, 200 μL of the test sample was added, and the total mass (m1) was accurately recorded. The bottles were then placed in the desiccator containing the desiccant for a total duration of t = 8 hours. For both the sample and control groups, the weighing bottles were removed from the desiccator at 2, 4, 6, and 8 hours; the stoppers were secured, and the weight (mt) was accurately recorded.

Moisturizing performance was evaluated based on the percentage of weight loss due to drying.

Test Conclusion: Under the specified test conditions, the results showed that the percentage weight loss for the sample group at 2, 4, 6, and 8 hours was lower than that of the negative control group, indicating that the sample possesses moisturizing properties.

  1. Gentle (Non-irritating),Suitable for sensitive skin

Test Protocol: This test involved 31 male and female subjects with sensitive skin (confirmed by a positive lactic acid sting test score of ≥3) who exhibited skin dullness, uneven texture, and facial redness upon visual assessment. There were 31 valid subjects, resulting in an efficacy rate of 93.94%. A questionnaire survey was used to evaluate claims regarding the product’s soothing properties, gentleness (non-irritating nature), and suitability for sensitive skin.

Based on evaluations by all subjects (N=31) after 28 days of continuous use, the subjects acknowledged the product’s soothing efficacy. Under the test conditions—involving 31 subjects aged 25–59 with sensitive skin using the product twice daily for 28 consecutive days—no adverse reactions were observed. These results support claims that the product is gentle, non-irritating, and suitable for sensitive skin.

Basis for determining efficacy: Statistical analysis was performed using the binomial distribution method via statistical software. The expected agreement value was set at 60%, and a 95% confidence interval was used to test the statistical significance of the survey questions. A significance level of p<0.05 indicates a statistically significant difference.

Correlation between the test item and efficacy claims: Soothing properties help alleviate conditions such as skin irritation. This test evaluated the product’s soothing efficacy based on improvements reported in response to relevant questions.

Gentle and non-irritating: Since cosmetics can potentially cause skin irritation, a product is deemed gentle and non-irritating if a human use test involving at least 30 subjects results in no adverse reactions throughout the entire usage period.

Suitable for sensitive skin: Individuals with sensitive skin often have a hyper-reactive skin state and are prone to irritation; therefore, not all cosmetics are suitable for this demographic. A product is deemed suitable for sensitive skin if a human use test involving at least 30 subjects with sensitive skin results in no adverse reactions throughout the entire usage period.

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